HDAC1 mAb
|
货号 |
P01L086 |
|
规格 |
100uL |
|
种属反应性 |
H, Bovine, Monkey |
|
应用 |
WB, IHC-P, IF/ICC, FC |
|
宿主 |
Rabbit |
|
说明书下载 |
|
Background
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CRESTmediated transcription in resting neurons.
