BAX mAb
|
货号 |
P02A100 |
|
规格 |
20ul/50ul/100ul |
|
种属反应性 |
Human，Rat，Mouse |
|
应用 |
WB, IHC-P，IP, FC |
|
宿主 |
Rabbit |
|
说明书下载 |
|
Background
The protein encoded by BAX (BCL2 associated X, apoptosis regulator) belongs to the BCL2 protein family. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis.
