P02A701 PD-L1 mAb
发布时间:2020-01-15 14:23 来源:市场部
PD-L1 mAb
货号 |
P02A701S/M/L |
规格 |
20ul/50ul/100ul |
种属反应性 |
Human |
应用 |
WB, IHC-P, IF/ICC,IP, FC |
宿主 |
Rabbit |
说明书下载 |
|
Background
PD-L1 is a member of the B7 family of cell surface ligands that regulate T cell activation and immune responses. PD-L1 protein contains extracellular IgV and IgC domains and a short, cytoplasmic region. Research studies demonstrate that PD-L1 is expressed in several tumor types, including melanoma, ovary, colon, lung, breast, and renal cell carcinomas. Expression of PD-L1 in cancer is associated with tumor infiltrating lymphocytes, which mediate PD-L1 expression through the release of interferon gamma.