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一抗系列
P02A701 PD-L1 mAb
发布时间:2020-01-15 14:23 来源:市场部
PD-L1 mAb
货号 P02A701S/M/L
规格 20ul/50ul/100ul
种属反应性 Human
应用 WB, IHC-P, IF/ICC,IP, FC
宿主 Rabbit
说明书下载


Background
       PD-L1 is a member of the B7 family of cell surface ligands that regulate T cell activation and immune responses. PD-L1 protein contains extracellular IgV and IgC domains and a short, cytoplasmic region. Research studies demonstrate that PD-L1 is expressed in several tumor types, including melanoma, ovary, colon, lung, breast, and renal cell carcinomas. Expression of PD-L1 in cancer is associated with tumor infiltrating lymphocytes, which mediate PD-L1 expression through the release of interferon gamma.